Palmitic acid 是在动物、植物和微生物中发现的最常见的饱和脂肪酸，具有抗肿瘤活性。它可诱导小鼠颗粒细胞中葡萄糖调节蛋白 78 和 CCAAT/增强子结合蛋白同源蛋白的表达。

Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.

As sources of PLA2, human recombinant sPLA2 (type IIA) is purified from CHO cells transfected with the PLA2 gene and rabbit recombinant platelet cPLA2 is obtained through its expression in baculovirus. The standard reaction mixture (200 μL) contained 100 mM Tris-HCl buffer (pH 9.0) with 6 mM CaCl2 and 20 nmol 1-acyl-[1-14C]-arachidonyl-sn-glycerophosphoethanolamine (2000 cpm/nmol) in the presence or absence of Tanshinone I. The reaction is started by adding 50 ng purified sPLA2 or cPLA2. After 20 min at 37°C, the free fatty acid generated is analysed. Under these standard conditions, the reaction mixture in the absence of Tanshinone I released approximately 10% of free fatty acid from the phospholipid substrate added[1].

57-10-3

C16H32O2

256.43

Cetylic acid;Hexadecoic acid;棕榈酸;hexadecanoic acid

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years