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Lyso-PAF C-16-d4
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Lyso-PAF C-16-d4图片
CAS NO:201216-37-7
包装与价格：
包装价格(元)
100 μg电议
500 μg电议
1mg电议

产品介绍
An internal standard for the quantification of LysoPAF C16
Cas No.201216-37-7
别名Lyso-platelet-activating factor C-16-d4
Canonical SMILESCCCCCCCCCCCCCCCCOC[C@@H](O)COP(=O)(O)OCC[N](C)(C)C
分子式C24H48D4NO6P
分子量485.7
溶解度DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml,Water: 20 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lyso-PAF C-16-d4contains four deuterium atoms at the 7, 7', 8, and 8' positions of the hexadecyl moiety. It is intended for use as an internal standard for the quantification of PAF C-16 by GC-or LC-mass spectrometry. Lyso-PAF C-16 can be formed by either the action of PAF-AH on PAF C-16,1or by the action of a CoA-independent transacylase on 1-O-hexadecyl-2-acyl-glycerophosphocholine.2,3Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway4or selective acylation with arachidonic acid by a CoA-independent transacylase.5

1.Stafforini, D.M., Prescott, S.M., and McIntyre, T.M.Human plasma platelet-activating factor acetylhydrolaseThe Journal of Biological Chemisty2624223-4230(1987) 2.Uemura, Y., Lee, T., and Snyder, F.A coenzyme A-independent transacylase is linked to the formation of platelet-activating factor (PAF) by generating the lyso-PAF intermediate in the remodeling pathwayThe Journal of Biological Chemisty2668268-8272(1991) 3.Venable, M.E., Nieto, M.L., Schmitt, J.D., et al.Conversion of 1-O-[3H]alkyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine to lyso platelet-activating factor by the CoA-independent transacylase in membrane fractions of human neutrophilsThe Journal of Biological Chemisty26618691-18698(1991) 4.Prescott, S.M., Zimmerman, G.A., and McIntyre, T.M.Platelet-activating factorThe Journal of Biological Chemisty26517381-17384(1990) 5.Venable, M.E., Olson, S.C., Nieto, M.L., et al.Enzymatic studies of lyso platelet-activation factor acylation in human neutrophils and changes upon stimulationThe Journal of Biological Chemisty2687965-7975(1993)