AKR1C1-IN-1 是高选择性AKR1C1抑制剂(Ki:4 nM)。

AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).

AKR1C1-IN-1 inhibits the metabolism of progesterone that in AKR1C1-overexpressed BAECs (IC50:460 nM).

4906-68-7

C13H9BrO3

293.11

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years