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2-Amino-5-bromo-benzonitrile
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2-Amino-5-bromo-benzonitrile图片
CAS NO:39263-32-6
包装与价格：
包装价格(元)
500mg电议
1 g电议

产品介绍
A heterocyclic building block
Cas No.39263-32-6
别名2-氨基-5-溴苯甲腈
Canonical SMILESNC1=C(C#N)C=C(Br)C=C1
分子式C7H5BrN2
分子量197
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Amino-5-bromo-benzonitrile is a heterocyclic building block.1,2It has been used in the synthesis of copper-ligand coordination complexes and 4-amino-3-benzimidazol-2-ylhydroquinolin-2-one-based multi-targeted receptor tyrosine kinase (RTK) inhibitors with anticancer activity.

1.Primik, M.F., GÖschl, S., Jakupec, M.A., et al.Structure-activity relationships of highly cytotoxic copper(II) complexes with modified indolo[3,2-c]quinoline ligandsInorg. Chem.49(23)11084-11095(2010) 2.Renhowe, P.A., Pecchi, S., Shafer, C.M., et al.Design, structure-activity relationships and in vivo characterization of 4-amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A novel class of receptor tyrosine kinase inhibitorsJ. Med. Chem.52(2)278-292(2009)