CKI-7 是一种有效且 ATP 竞争性的酪蛋白激酶 1 抑制剂，IC50为 6 μM，Ki为 8.5 μM。它选择性抑制Cdc7激酶，还抑制SGK，S6K1以及MSK1。

CKI-7 2HCl is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 2HCl also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.

1177141-67-1

C11H14Cl3N3O2S

358.67

CKI-7 2HCl;CKI7 2HCl;N-(2-氨基乙基)-5-氯异喹啉-8-磺酰胺二盐酸盐;CKI 7 dihydrochloride;CKI7 dihydrochloride;CKI 7 2HCl;CKI-7 dihydrochloride

DMSO:65 mg/ml (181.23 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years