SBC115076 是前蛋白转化酶枯草杆菌蛋白酶/ kexin 9型(PCSK9)抑制剂。其中PCSK9 是一种前蛋白转化酶，在 LDL 受体代谢中的重要物质。

SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.

In HepG2 cells, SBC-115076 increases the uptake of Fluorescent Dil-LDL. [1]

In mice that are fed high fat diet, SBC-115076 (8 mg/kg) lowers cholesterol levels by 32%. [1]

489415-96-5

C31H33N3O5

527.61

SBC115076

DMSO:93 mg/mL (176.3 mM)
H2O:<1 mgml
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years