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Diethyl-pythiDC
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Diethyl-pythiDC图片
CAS NO:1821370-70-0
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Diethyl-pythiDC 是一种胶原蛋白脯氨酰 4-羟化酶抑制剂。

产品描述

Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.

体外活性

In MDA-MB-231 cells, Diethyl-pythiDC inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. None of the esterified Diethyl-pythiDC exhibited cytotoxic activity at high micromolar concentrations. Cells treated with dihydroxybenzoate demonstrate a strong iron-deficient phenotype. In contrast, cells treated with Diethyl-pythiDC appear to be normal at concentrations as high as 500 μM. Treatment with Diethyl-pythiDC and low levels of diethyl pyimDC does not affect the level of TfR, HIF-1α, or ferritin[1].

Cas No.

1821370-70-0

分子式

C14H14N2O4S

分子量

306.34

储存和溶解度

DMSO:33 mg/mL (107.72 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years