BC-1382 是E3泛素连接酶HECTD2抑制剂，能够特异性破坏 HECTD2/PIAS1 相互作用 (IC50≈ 5 nM)。BC-1382具有抗炎活性。

BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).

BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS)- and Pseudomonas aeruginosa-induced lung inflammation.

1013753-99-5

C23H29N3O5S

459.56

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years