PTP1B-IN-9 是一种泛素-蛋白酶体系统(UPS)应激源，是通过抑制 20S 蛋白酶体催化活性物质上游泛素介导的蛋白质降解而产生。它能够在不影响 20S 蛋白酶体催化活性的情况下触发泛素蛋白酶体系统 (UPS) 应激反应。
产品描述
PTP1B-IN-9 is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity.
体外活性
PTP1B-IN-9 reduces the cell viability of exponentially growing HeLa cervical cancer cells in a dose-dependent fashion with an IC50 value of 2 μM[1].
Cas No.
145888-79-5
分子式
C19H13Cl4NO
分子量
413.13
别名
PTP1B-IN-9
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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