Saikogenin A 是一种二肽基肽酶 IV 抑制剂，可从中药柴胡中提取。

Saikogenin A is a dipeptidyl peptidase-4 inhibitor.

Saikogenin A has a certain inhibitory effect on the enzyme DPP-IV. At a concentration of 20 μg/mL DPP-IV inhibition is 47.6% [1].

Saikogenin A is less effective in adrenalectomized rats than in normal rats in reducing the carrageenin-induced edema. The anti-inflammatory action of Saikogenin A is due to an increase in corticosterone caused by the release of arenocorticotropic hormone and a direct effect on the process of inflammation [2].

5092-09-1

C30H48O4

472.7

DMSO:60 mg/ml (126.93 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years