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CORM 2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:22594-69-0
包装:100mg
市场价:676元

产品介绍
CORM 2 是释放 CO 的药理学供体。
Cas No.22594-69-0
别名三羰基二氯代钌二聚物,CORM-2
Canonical SMILES[Cl-][Ru++]1([Cl-][Ru++]([Cl-])([Cl-]1)(C#[O])(C#[O])C#[O])(C#[O])(C#[O])C#[O]
分子式C6Cl4O6Ru2
分子量512.01
溶解度Soluble in DMSO
储存条件4°C, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Carbon monoxide-releasing molecule. Causes vasodilatation in isolated aortic rings in vitro. Cytotoxic to smooth muscle cells in vitro after prolonged (24h) exposure. Exhibits antihypertensive effects in vivo. Reduces tight-junction disruption in intestinal mucosa in a rat sepsis model.

Zhang et al (2015) Carbon monoxide-releasing molecule-2 reduces intestinal epithelial tight-junction damage and mortality in septic rats. PLoS One 10 e0145988 PMID:26720630 |Motterlini et al (2002) Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities. Circ.Res. 90 E17 PMID:11834719