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Propargyl-PEG4-alcohol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Propargyl-PEG4-alcohol图片
CAS NO:87450-10-0
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
Propargyl-PEG4-alcohol 是一种 PROTAC linker,属于 PEG 类。Propargyl-PEG4-alcohol 可用于合成一系列 PROTAC 分子。
Cas No.87450-10-0
别名丙炔基-四聚乙二醇
Canonical SMILESC#CCOCCOCCOCCOCCO
分子式C11H20O5
分子量232.27
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Propargyl-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.