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Mal-PEG1-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mal-PEG1-acid图片
CAS NO:760952-64-5
包装与价格:
包装价格(元)
100mg电议
250mg电议

产品介绍
Mal-PEG1-acid是一种不可降解 (non-cleavable) 的含 1 个单元 PEG 的 ADC linker,可用于合成 抗体偶联药物 (ADC)。
Cas No.760952-64-5
Canonical SMILESO=C(O)CCOCCN1C(C=CC1=O)=O
分子式C9H11NO5
分子量213.19
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[1]. Karpov AS, et al. Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody-Drug Conjugates. ACS Med Chem Lett. 2018 Jun 28;9(8):838-842.