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Beta-Tocopherol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Beta-Tocopherol图片
CAS NO:148-03-8
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
BETA-生育酚
β-生育酚
产品介绍
Beta-TocopHERol 对由 phorbol 12-myriSTATe 13-acetate (PMA) 诱导的人红白血病细胞 (HEL) 粘附有影响。

产品描述

Beta-Tocopherol shows effect on human erythroleukemia cell (HEL) adhesion induced by phorbol 12-myristate 13-acetate (PMA).

体外活性

Adhesion induced by PMA stimulation was prevented by 44.5% by physiological concentrations of alpha-tocopherol. Under the same experimental conditions, Beta-Tocopherol, an analogue of alpha-tocopherol, produced 11% inhibition of adhesion. Cell response gradually increased from 0 to 24 h of alpha-tocopherol treatment. Only a slight time dependency of Beta-Tocopherol inhibition was observed. Another human erythroleukemia cell line (K562) and the human monocyte tumor cell line U937 showed 5.0 and 11.2% inhibition, respectively. Similar to alpha-tocopherol, the protein kinase C inhibitor, Calphostin C, and the MAPK inhibitor, PD98059, prevented PMA-induced cell adhesion. An inhibition of ERK-1 phosphorylation was observed for alpha-tocopherol only in HEL, implying that MAP kinase pathway is involved in this cell line.

Cas No.

148-03-8

分子式

C28H48O2

分子量

416.68

别名

BETA-生育酚;β-生育酚

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years