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Cornuside
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cornuside图片
CAS NO:131189-57-6
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Comuside
7-O-Galloylsecologanol
山茱萸新苷
7-Galloylsecologanol
产品介绍
Cornuside 是从山茱萸的果实中分离出的环烯醚萜苷,可用于炎症疾病的研究和促进血液循环。 它通过下调MAPK和NF-κB信号通路抑制肥大细胞介导的过敏反应,用于炎性过敏性疾病中的潜能。

产品描述

1. Cornuside has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardial I/R and protect the liver from CCl4-induced acute hepatotoxicity, by reducing oxidative stress and suppressing inflammatory responses. 4. Cornuside has anti-inflammatory activity by downregulations of iNOS and COX-2 due to NF-κB inhibition as well as the negative regulation of ERK1/2, p38, and JNK1/2 phosphorylations in RAW 264.7 cells. 5. Cornuside has protective potential against cerebral ischemic injury, may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity, and improvements in mitochondrial energy metabolism and antioxidant properties.

Cas No.

131189-57-6

分子式

C24H30O14

分子量

542.49

别名

Comuside;7-O-Galloylsecologanol;山茱萸新苷;7-Galloylsecologanol

储存和溶解度

DMSO:Soluble
Ethanol:Soluble
Pyridine, Methanol, etc.:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years