BAY-6035 是 SET 和 MYND 结构域蛋白 3 (SMYD3) 的抑制剂。 BAY-6035 的选择性比其他组蛋白甲基转移酶高 100 倍以上。

BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases.

BAY-6035 inhibits methylation of MEKK2 peptide in a cell-free assay and in cells with IC50s of 88 and 70 nM, respectively[1].

2247890-13-5

C22H28N4O3

396.48

DMSO:100 mg/mL (239.61 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years