| CAS NO: | 64567-60-8 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| Cas No. | 64567-60-8 |
| 别名 | 4-羟基沙利度胺 |
| Canonical SMILES | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(O)=C3)=O |
| 分子式 | C13H10N2O5 |
| 分子量 | 274.23 |
| 溶解度 | DMSO: 62.5 mg/mL (227.91 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs[1]. [1]. Megan G Marks, et al. Effects of Putative Hydroxylated Thalidomide Metabolites on Blood Vessel Density in the Chorioallantoic Membrane (CAM) Assay and on Tumor and Endothelial Cell Proliferation. Biol Pharm Bull. 2002 May;25(5):597-604. |
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