Thalidomide5-fluoride是基于沙利度胺的Cereblon配体(ligand)，通过linker与IRAK4蛋白配体结合形成PROTACIRAK4degrader-1。
| Cas No. | 835616-61-0 |
| Canonical SMILES | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(F)=C3)=O |
| 分子式 | C13H9FN2O4 |
| 分子量 | 276.22 |
| 溶解度 | DMSO: 83.33 mg/mL (301.68 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Thalidomide 5-fluoride is Thalidomide-based cereblon ligand that incorporates to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1. |
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