CAS NO: | 2922-56-7 |
包装 | 价格(元) |
10mM (in 1mL Water) | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Cas No. | 2922-56-7 |
Canonical SMILES | O=C(O)CNC([C@H](CSC)NC(CC[C@@H](C(O)=O)N)=O)=O |
分子式 | C11H19N3O6S |
分子量 | 321.35 |
溶解度 | Water: 35.71 mg/mL (111.12 mM) |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | S-Methylglutathione is an S-substitued glutathione and a stronger nucleophile than GSH[1]. S-Methylglutathione has inhibitory effect on glyoxalase 1[2]. S-Methylglutathione (GS-Me) is a stronger nucleophile than GSH, which is rationalized by the more positive inductive effect of the methyl group[1]. [1]. Foye WO, et al. Synthesis and evaluation of N-alkanoyl-S-benzyl-L-cysteinylglutamic acid esters as glyoxalase I inhibitors and anticancer agents. J Pharm Sci. 1984 Apr;73(4):559-61. [2]. Milos I. Djuran,et al. Reactivity of chloro- and aqua(diethylenetriamine)platinum(II) ions with glutathione, S-methylglutathione, and guanosine 5'-monophosphate in relation to the antitumor activity and toxicity of platinum complexes. Inorg. Chem. 1991, 30, 12, 2648-2652 |