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Pantoprazole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pantoprazole图片
CAS NO:102625-70-7
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
泮托拉唑
SKF96022
BY1023
产品介绍
Pantoprazole 是一种质子泵抑制剂,用于短期治疗由胃食管反流病引起的食管糜烂和溃疡。它联合阿霉素可显著增加肿瘤生长延迟。它是一种取代的苯并咪唑,是H+/K+-ATPase抑制剂,可改善 pH 值稳定性,具有抗分泌和抗溃疡的作用。

产品描述

Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

体外活性

PPZ(Pantoprazole) inhibits the proliferation of tumor cells, induces apoptosis and downregulates the expression of PKM2, which contributes to the current understanding of the functional association between PPZ and PKM2(The human M2 isoform of pyruvate kinase)[2]. Ex vivo studies showed that pantoprazole inhibited TOPK activities in JB6 Cl41 cells and HCT 116 colorectal cancer cells. Moreover, knockdown of TOPK in HCT 116 cells decreased their sensitivities to pantoprazole.

Cas No.

102625-70-7

分子式

C16H15F2N3O4S

分子量

383.37

别名

泮托拉唑;SKF96022;BY1023

储存和溶解度

DMSO:71 mg/mL (185.2 mM)
H2O:<1 mgml
Ethanol:71 mg/mL (185.2 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years