Leptomycin B是一种抗真菌抗生素，可阻断真核细胞周期，抑制蛋白出核转运。Leptomycin 通过半胱氨酸残基处的共价修饰使CRM1/exportin 1失活。它

Leptomycin B is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue.

87081-35-4

C33H48O6

540.73

LMB;CI 940;来普霉素B

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years