TRPV4 agonist-1 free base 是有效的瞬时受体电位香草酸亚型 4 激动剂， hTRPV4 Ca2+实验中EC50值为60 nM。

TRPV4 agonist-1 free base is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).

Significantly increased potency (ECmax: 20 nM in the SOX9 reporter assay) exhibited by TRPV4 agonist-1.

2314467-59-7

C25H22F2N4O2

448.474

OUN67600

DMSO:83.33 mg/mL (185.81 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years