ValategRast hydrochloride是一种有效的整联蛋白 α4β1 (VLA-4) 和 α4β7 双重拮抗剂。ValategRast hydrochloride 可用于慢性阻塞性肺疾病 (COPD) 和哮喘的研究。

Valategrast hydrochloride, a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.

Valategrast hydrochloride contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS)[2].

828271-96-1

C30H33Cl4N3O4

641.41

RO-0272441;RO0272441;Valategrast HCl;RO-27-2441;R-411;RO27244;R411

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years