P8RI acetate 是 CD31 的仿生肽和 CD3 的激动剂。 P8RI acetate 通过恢复 CD31 抑制途径显示出免疫抑制作用。

P8RI acetate is a biomimetic peptide of CD31 and an agonist of CDP8RI acetate shows an immunosuppressive effect through the restoration of the CD31 inhibitory pathway.

P8RI acetate maintains bioactivity and confers resistance toward plasma proteases[2].

In Apo E -/- mice (male, 28-week-old) implanted with Ang II-releasing pumps (a model of experimental acute aortic dissection and intramural hematoma (ADIM)), P8RI acetate (2.5 mg/kg; s.c.) prevents aneurysmal transformation by promoting the resolution of intramural hematoma and the production of collagen in dissected aortas[3].

T39615L

C53H81N13O11

1076.29

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years