BTS 是一种选择性骨骼肌肌球蛋白 II 亚片段 1 (S1) ATPase 活性抑制剂，可特异性抑制骨骼肌快速纤维的收缩。它对肌动蛋白和 Ca2+刺激的肌球蛋白 S1 ATPase 的IC50值约为 5 μM。

BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .

BTS is remarkably specific, as it was much less effective in suppressing contraction in rat myocardial or rabbit slow-twitch muscle, and did not inhibit platelet myosin II.?The isolation of BTS and the recently discovered Eg5 kinesin inhibitor, monastrol, suggests that motor proteins may be potential targets for therapeutic applications.

1576-37-0

C14H15NO2S

261.34

N-Benzyl-p-toluenesulfonamide;N-Tosylbenzylamine;N-苄基-对甲苯磺酸胺

DMSO:33.33 mg/mL (127.54 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years