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Ferrous bisglycinate
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Ferrous bisglycinate图片
CAS NO:20150-34-9
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
250mg电议

产品介绍

Ferrousbisglycinate是一种具有口服活性的铁强化剂和补充剂。Ferrousbisglycinate可用于缺铁性贫血的研究。

Cas No.20150-34-9
别名甘氨酸亚铁
Canonical SMILESO=C1[O-][Fe+2]2([O-]C(CN2)=O)NC1
分子式C4H6FeN2O4
分子量201.95
溶解度Water: 35.71 mg/mL (176.83 mM)
储存条件4°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
产品描述

Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia[1][2].

Ferrous bisglycinate (25-200 μM; 2 h) does not affect the Caco-2 cells viability[2].Ferrous bisglycinate (25 μM; 2 h) increases ferritin content in the Caco-2 cells[2]. Cell Viability Assay[2] Cell Line: Caco-2 cells

Ferrous bisglycinate (500 mg/kg iron; p.o.) exerts a protective effect on colitis in mice[3]. Animal Model: Female C57BL/6 mice are induced colitis by dextran sodium sulfate (DSS)[3]

References:
[1]. Ferrari P, et, al. Treatment of mild non-chemotherapy-induced iron deficiency anemia in cancer patients: comparison between oral ferrous bisglycinate chelate and ferrous sulfate. Biomed Pharmacother. 2012 Sep; 66(6): 414-8.
[2]. Yu X, et, al. Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells. Nutrients. 2019 Feb 26; 11(3): 485.
[3]. Constante M, et, al. Iron Supplements Modulate Colon Microbiota Composition and Potentiate the Protective Effects of Probiotics in Dextran Sodium Sulfate-induced Colitis. Inflamm Bowel Dis. 2017 May; 23(5): 753-766.