| CAS NO: | 865273-97-8 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 865273-97-8 |
| Canonical SMILES | O=C(O)C1=CC=C(OC)C(S(=O)(NC2=CC(C(F)(F)F)=CC=C2N3CCCCC3)=O)=C1 |
| 分子式 | C20H21F3N2O5S |
| 分子量 | 458.45 |
| 溶解度 | DMSO: 250 mg/mL (545.32 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 competitively inhibits ERAP1 activity towards a nonamer peptide representative of physiological substrates[1]. ERAP1-IN-1 allosterically activates ERAP1's hydrolysis of fluorogenic and chromogenic amino acid substratesv[1].ERAP1-IN-1 (50 µM) exhibits specific inhibition of ERAP1 in the cellular context[1]. [1]. Maben Z, et al. Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1. J Med Chem. 2019 Dec 30. |
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