8-Bromo-cAMP(sodium salt) 是一种环 AMP 依赖性蛋白激酶 (PKA) 激活剂，是一种环 AMP 类似物。

8-Bromo-cAMP is a long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase.

在支气管上皮细胞中,8-Bromo-cAMP减少HDE刺激的肿瘤坏死因子(TNF)-α-转化酶(TACE；ADAM-17)活性和随后的TNF-α释放。8-Bromo-cAMP提高人新生包皮成纤维细胞(HFF1)的重编程效率。

76939-46-3

C10H10BrN5NaO6P

430.08

8-溴腺苷-3',5'-环单磷酸钠;8-Bromo-cAMP;8-Bromo-cAMP(sodium salt);8-Br-Camp sodium salt

H2O:80 mg/mL (186.01 mM),warmed
Ethanol:<1 mgml
DMSO:35 mg/mL (81.38 mM),warmed
Powder: -20°C for 3 years
In solvent: -80°C for 2 years