AZ-DYRK1B-33 是高选择性的DYRK1B激酶抑制剂，其IC50=7 nM。

AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.

Administration of AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM and no effect in sensitization[1].

1679330-37-0

C19H16N4

300.36

3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine

DMSO:120 mg/mL (399.52 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years