AWL-II-38.3是一种有效的ephrin-A受体激酶抑制剂,且AWL-II-38.3对b-Raf和Src家族激酶均没有显著的细胞活性。
产品描述
AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf [1] [2].
体外活性
AWL-II-38.3 fits to LIMK2 and LIMK1 ATP-binding and substrate-binding pockets [2] .
Cas No.
1135205-94-5
分子式
C23H18F3N5O3
分子量
469.42
储存和溶解度
DMSO:65 mg/mL (138.47 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years