4'-Methoxyresveratrol 是一种多酚类化合物，来源于双翅目植物中，具有抗雄激素、抗真菌和抗炎症作用。它能抑制 RAGE- 介导的 MAPK/NF-Κb 信号通路，并激活 NLRP3 炎性体，从而缓解 AGE- 诱导的炎症。

4'-Methoxyresveratrol is a natural product form the roots of Rheum palmatum L,has significant hypoglycemic, anti-inflammatory, and antioxidant effects.4'-Methoxyresveratrol alleviates AGE-induced inflammation through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation.

4'-Methoxyresveratrol significantly abated the activation of NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome including NLRP3 and cleaved caspase-1 and reduced the secretion of mature IL-1β. The anti-inflammatory effect of 4'-Methoxyresveratrol is mainly through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation. 4'-Methoxyresveratrol could be a novel therapeutic agent for inflammation-related diseases.

33626-08-3

C15H14O3

242.274

白藜芦醇-4'-甲醚;4'-O-Methylresveratrol

DMSO:48 mg/mL (198.13 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years