BpV(HOpic) 是 PTEN 选择性抑制剂，IC50=14 nM。Nanocarrier-BpV(HOpic) 具有神经保护作用。

bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).

1 μM BpV(Hopic) is capable of enhancing the migration of C2C12 myoblasts by approximately 40 % in the presence of myotube conditioned media, without significantly affecting their capacity to differentiate and fuse into multinucleated myotubes.?Improved migration of myoblasts treated with 1 μM BpV(Hopic) was associated with activation of PI3K/AKT and MAPK/ERK pathways, while their inhibition with either LY294002 or UO126, respectively, resulted in a reduction of C2C12 migration back to control levels[1]

722494-26-0

C6H4K2NO8V

347.235

bpV (HOpic)

H2O:10 mM
DMSO:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years