TC-S 7005是一种有效的Polo样激酶的抑制剂，PLK1、PLK2和PLK3的IC50值分别为214 nM，4 nM和24 nM。

TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s: 214 nM, 4 nM and 24 nM for Plk1, Plk2, and Plk3).

In human SR fibroblasts, TC-S 7005(1 μM) obviously causess myofibroblast differentiation and decrease fibroblast proliferation rates [2].

1082739-92-1

C21H17N3O3

359.385

DMSO:100 mg/mL (278.3 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years