PF-06882961 Tris 是一种口服生物可利用的胰高血糖素样肽-1 受体 (GLP-1R) 激动剂。

PF-06882961 Tris is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.

Biological in-vitro testing revealed favorable ADME and pharmacological profiles for the best PF-06882961 Tris[1].

PF-06882961 Tris shows mild to moderate damage to the heart, moderate to severe effects on the thymus gland (which helps with managing infection), mild to moderate stomach ulcers at the highest dose level given in the rat[2].

2230198-03-3

C35H41FN6O7

676.746

UNII-2HJV78O0SS

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years