NE-100 hydrochloride 是选择性sigma-1 受体拮抗剂，IC50为 4.16 nM。它在体内具有抗精神病活性。它也能抑制内质网应激诱导的海马细胞死亡。

NE100 HCl is a potent and selective antagonist of σ1 (IC50 = 4.16 nM) with antipsychotic activity. NE100 HCl also suppresses ER stress-induced hippocampal cell death.

149409-57-4

C23H34ClNO2

391.98

NE 100 Hydrochloride;NE 100 HCl;NE-100 HCl;NE-100 Hydrochloride;NE100 Hydrochloride

H2O:15mg/mL,Need ultrasonic and warming and heat to 60°C
DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years