您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > Apalutamide-COOH
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Apalutamide-COOH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Apalutamide-COOH图片
CAS NO:1332391-04-4
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Apalutamide-COOH可用于合成Apalutamide。Apalutamide是有效,竞争性的雄激素受体(AR)拮抗剂,IC50为16nM。
Cas No.1332391-04-4
Canonical SMILESO=C(O)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43CCC4)C=C1F
分子式C20H12F4N4O3S
分子量464.39
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Apalutamide-COOH can be used to synthesis Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].

[1]. Nicholas D. Smith, et al. Androgen receptor modulators and uses thereof. WO2011103202A2.