Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base) 是一种有效的选择性缓激肽 B1 受体激动剂(兔主动脉中的 EC50 = 9.02 nM),对氨肽酶、激肽酶 I 和 II (ACE) 以及中性内肽酶切割具有抗性。在体内表现出降血压和血管生成活性。
产品描述
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate is a potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. Exhibits hypotensive and angiogenic activity in vivo.
Cas No.
TP1917L1
分子式
C49H70N12O13
分子量
1035.15
别名
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base)
储存和溶解度
DMSO:5 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years