ESI-05 是特异性的 cAMP 直接激活交换蛋白 2 (EPAC2) 拮抗剂(IC50:0.4 μM)，能够抑制 cAMP 诱导的 EPAC2 的活化，并 EAPC2 介导的 Rap1 的活化。

ESI-05 is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.

5184-64-5

C16H18O2S

274.38

NSC 116966

DMSO:83.33 mg/mL (303.70 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years