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Terlipressin acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Terlipressin acetate图片
CAS NO:1884420-36-3
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
Terlipressin diacetate anhydrous
Terlipressin acetate anhydrous
醋酸特利加压素
产品介绍
Terlipressin acetate 是一种高度选择性的加压素 V1 受体激动剂,对氧和葡萄糖剥夺/再氧合 (OGD/R) 诱导的肠上皮细胞损伤 (IEC-6) 具有抗炎和抗氧化作用,可用于肝肾综合征和耐去甲肾上腺素的败血性休克的研究。

产品描述

Terlipressin, a highly selective vasopressin V1 receptor agonist, on oxygen and glucose deprivation/re-oxygenation (OGD/R)-induced damage in intestinal epithelial cells (IEC-6).Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research.

体外活性

Incubation with 25 nM terlipressin significantly improved cell viability, proliferation and apoptosis. Furthermore, terlipressin inhibited the secretion of TNF-α and 15-F2t-isoprostane from IEC-6 cells following OGD/R[1].

体内活性

Using a mouse nonlethal hepatic IR model, we found terlipressin administration significantly ameliorated IR-induced liver apoptosis, necrosis and inflammation[2].

Cas No.

1884420-36-3

分子式

C56H82N16O19S2

分子量

1347.49

别名

Terlipressin diacetate anhydrous;Terlipressin acetate anhydrous;醋酸特利加压素

储存和溶解度

DMSO:95mg/mL (70.50mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years