BIRT-377 是 ICAM-1 和 LFA-1 的负变构和口服生物利用度抑制剂（Ki = 25.8 nM）。 BIRT-377 抑制 IL-2 的产生，可用于有关炎症和免疫疾病的研究。

BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1(Ki = 25.8 nM). BIRT-377 inhibits the production of IL-2 and can be used in studies about inflammatory and immune disorders.

213211-10-0

C18H15BrCl2N2O2

442.13

BIRT 377;BIRT377

DMSO:90mg/mL (203.6mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years