Prolyl Endopeptidase Inhibitor 1

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

86925-97-5

包装与价格：

产品介绍

Prolyl Endopeptidase Inhibitor 1 (Boc-Pro-prolinal) 是一种有效的脯氨酸内肽酶 (PEP; PE) 抑制剂，Ki 值为 15 nM。Prolyl endopeptidase-IN-1 具有抗遗忘作用。

Cas No.	86925-97-5
别名	Boc-Pro-prolinal; (Boc)-Prolyl-prolinal; BPP
Canonical SMILES	O=C(N1[C@H](C(N2[C@H](C=O)CCC2)=O)CCC1)OC(C)(C)C
分子式	C₁₅H₂₄N₂O₄
分子量	296.36
溶解度	Soluble in DMSO
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Prolyl Endopeptidase Inhibitor 1 (Boc-Pro-prolinal) is a potent prolyl endopeptidase (PEP; PE) inhibitor, with a Ki value of 15 nM. Prolyl Endopeptidase Inhibitor 1 has anti-amnesic effect[1]. Prolyl Endopeptidase Inhibitor 1 (Boc-Pro-prolinal) strongly inhibits the mammalian prolyl endopeptidase with a Ki value of nM order, while the Ki value for the microbial enzyme is only of microM order (Ki=3.2 μM for Flavobacterium)[1]. [1]. Yoshimoto T, et al. Specific inhibitors for prolyl endopeptidase and their anti-amnesic effect. J Pharmacobiodyn. 1987 Dec;10(12):730-5. [2]. Yoshimoto T, et al. Comparison of inhibitory effects of prolinal-containing peptide derivatives on prolyl endopeptidases from bovine brain and Flavobacterium. J Biochem. 1985 Oct;98(4):975-9.