(S,R,S)-AHPC-C4-NH2 hydrochloride 是一种合成的 E3 连接酶配体- linker 偶联物，包含基于 (S,R,S)-AHPC 的 VHL 配体和 linker。

(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.

PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1].

2245697-83-8

C27H40ClN5O4S

566.16

VH032-C4-NH2 hydrochloride;VHL Ligand-Linker Conjugates 13;E3 ligase Ligand-Linker Conjugates 28

H2O:50 mg/mL (88.31 mM)
DMSO:109.6 mg/mL (193.58 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years