Isolithocholic Acid (β-Lithocholic acid) 是石胆酸的一种同分异构体。Isolithocholic Acid 是一种胆酸,由 Lithocholic acid 或 Lithocholic acid 3α-sulfate 经微生物代谢形成。
产品描述
Isolithocholic Acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic Acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate.
体外活性
Isolithocholic Acid at 0.01 % does not inhibit spore germination and outgrowth of CF5 and M120, but it significantly inhibits at the higher concentration (0.1 %). Isolithocholic Acid (0.00003 %) prevents growth of CD196, M68, CF5, 630, and BI9 and significant decreases strains CF5, BI9, M120, and 630 in toxin activity. Isolithocholic Acid (0.0003 %) makes that all strains displays a significant decrease in toxin activity, except for R20291 and M120[3].
体内活性
The levels of fecal Isolithocholic Acid shows obvious decreases from day 28 onward in the high fat diet (HFD) group compared with rats fed a normal diet[4].
Cas No.
1534-35-6
分子式
C24H40O3
分子量
376.57
别名
3-Epilithocholic acid;3β-Hydroxy-5β-cholanic acid;β-Lithocholic acid
储存和溶解度
Ethanol:Slightly soluble
Chloroform:Slightly soluble
Methanol:Slightly soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years