Cholesteryl linoleate 是低密度脂蛋白和动脉粥样硬化病变中主要的胆固醇酯。它存在于 LDL 中的胆固醇酯,利用 LDL 受体相关蛋白转移到表达 15-脂氧合酶的巨噬细胞和 CHO 细胞的质膜,被氧化形成胆固醇亚油酸氢过氧化物。
产品描述
Cholesteryl linoleate is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via LDL receptor-related protein (LRP), where it undergoes oxidation to form cholesteryl linoleate hydroperoxides.
Cas No.
604-33-1
分子式
C45H76O2
分子量
649.101
别名
胆甾烯基亚油酸酯;Linoleic Acid cholesteryl ester;Cholesterol Linoleate;CE(18:2(9Z,12Z))
储存和溶解度
DMSO:Soluble
Chloroform:10 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years