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Magnolioside
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Magnolioside图片
CAS NO:20186-29-2
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
七叶苷甲基醚
6-甲氧基香豆素-7-0-BETA-D-吡喃葡萄糖苷
产品介绍
Magnolioside 是分离自Angelica gigas Nakai(Umbelliferae) 中,对谷氨酸诱导的毒性有显著的神经保护作用。 它显示出对金黄色葡萄球菌 CIP 53.154 的中等抗菌活性。它具有抗疟原虫活性,对氯喹敏感的恶性疟原虫菌株具有强烈的生长抑制作用。

产品描述

Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CIP 53.154.Magnolioside exhibits significant neuroprotective activities against glutamate-induced toxicity.

体外活性

Using antiplasmodial activity-guided fractionation, five coumarins, marmesinin (1), nodakenin (2), skimmin (3), apiosylskimmin (4), and Magnolioside (5), were isolated and evaluated for in vitro antiplasmodial activity, as well as for their cytotoxic potential on SK-OV-3 cancer cell lines. Compounds 1 and 5 showed notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum with IC(50) values of 5.3 and 8.2 μM. The compounds showed no significant cytotoxicity (IC(50) >100 μM) toward the SK-OV-3 cancer cell line[1]

Cas No.

20186-29-2

分子式

C16H18O9

分子量

354.31

别名

七叶苷甲基醚;6-甲氧基香豆素-7-0-BETA-D-吡喃葡萄糖苷

储存和溶解度

DMSO:55 mg/ml (155.23 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years