您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > beta-Amyrone
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
beta-Amyrone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
beta-Amyrone图片
CAS NO:638-97-1
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
β-Amyron
β-香树脂酮
产品介绍
beta-Amyrone 对基孔肯雅病毒复制具有抗真菌活性,EC50 为 86 uM。 beta-Amyrone 通过抑制 COX-2 的表达而具有抗炎活性。 beta-Amyrone 表现出抗α-葡萄糖苷酶抑制活性和中等 AChE 活性。 β-Amyrone 可用于炎症、感染和肥胖等疾病的研究。

产品描述

beta-Amyrone has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity.

体外活性

beta-Amyrone inhibits α-glucosidase AChE and fungal activity with IC50 values of 25 μM, 23 μM and 8 μg/mL, respectively[1]. In LPS-stimulated J774 cells, beta-Amyrone (2.5, 5, 10 μg/mL) inhibits NO production with an IC50 value of 4.61 μg/mL without obvious effects on cell viability[4]. beta-Amyrone (10 μg/mL) inhibits IL-6, IL-10 levels, and COX-2 expression at the dose of 10 μg/mL[4].

体内活性

In ear phenol-induced edema in Balb C mice, beta-Amyrone (0.1, 0.3, 0.6 mg/kg) inhibits ear edema formation in a dose-related manner[4].

Cas No.

638-97-1

分子式

C30H48O

分子量

424.7

别名

β-Amyron;β-香树脂酮

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years