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Gomisin D
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Gomisin D图片
CAS NO:60546-10-3
包装与价格:
包装价格(元)
10 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
戈米辛 D
戈米辛D
产品介绍
Gomisin D 是一种分离自五味子中的木脂素。它抑制 UDP-葡糖醛酸基转移酶活性,清除 ABTS(+) 自由基。 它是生脉散和参芪降糖颗粒的质量标志物,具有成为抗糖尿病药和抗阿尔茨海默病药的潜力。

产品描述

Gomisin D is a natural product.Gomisin D is used as a quality marker of Shengmai San and shenqi Jiangtang Granule.Gomisin D is a potential antidiabetic and anti-Alzheimer’s agent.

体外活性

Using exhaustive chromatographic separation we have isolated (-)-tigloyl-deangeloyl-gomisin F as a novel dibenzocyclooctadiene lignan from schisandra chinensis. With the help of HPLC, we further isolated (+)-schisandrin, (+)-deoxyschisandrin, (+)-γ-schisandrin, (-)-gomisin J, (+)-gomisin A, (-)-gomisin N, (-)-tigloyl-gomisin P, (-)-wuweizisu C, (-)-Gomisin D, rubrisandrin A, (-)-gomisin G, (+)-gomisin K (3) and (-)-schisantherin C. A full NMR description of (-)-schisantherin C was carried out with the aim to confirm previous reports of its structure. Compounds isolated were identified on the basis of UV, IR, (1)H- and (13)C-NMR and MS. The cytotoxicity of lignans was tested for the BY-2 cell line alone and as a synergistic effect with the cytotoxic agent camptothecin.

Cas No.

60546-10-3

分子式

C28H34O10

分子量

530.56

别名

戈米辛 D;戈米辛D

储存和溶解度

DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years