Crocin 是从Crocus sativus柱头中分离出的主要成分,是一种营养保健品,具有抗炎,抗癌,抗抑郁和抗惊厥等强大的药理作用。
产品描述
Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne or tranquilizer. Crocin suppresses tumor necrosis factor (TNF)alpha-induced apoptosis of pheochromocytoma (PC12) cells by modulating mRNA expressions of Bcl-2 family proteins, which trigger downstream signals culminating in caspase-3 activation followed by cell death. Crocin prevented the activation of nSMase by enhancing the transcription of gamma-glutamylcysteinyl synthase, which contributes to a stable glutathione supply that blocks the activity of nSMase.
Cas No.
42553-65-1
分子式
C44H64O24
分子量
976.972
别名
藏红花;藏红花素;Alpha-Crocin;Gardenia Yellow;西红花苷
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years