Remoxipride hydrochloride 是一种选择性的 D2 受体拮抗剂，对 D2 受体、D1 受体和 α1-肾上腺素能受体的 IC50 分别为 1.57 μM、＞100 μM 和 42 μM。

Remoxipride hydrochloride is a selective antagonist of D2 receptor with IC50s of 1.57 μM, ＞100 μM and 42 μM for D2 receptor, D1 receptor and α1-adrenoceptor.

In male Sprague-Dawley rats, Remoxipride hydrochloride (0.1-100 μM/kg; i.p.) blockes apomorphine-induced hyperactivity and dose-dependent blockades apomorphine-induced behaviors. In beagle dogs, Remoxipride hydrochloride (0.25-5 μM/kg; gavage) blockes apomorphine-induced vomiting[1].

73220-03-8

C16H24BrClN2O3

407.73

Roxiam;Remoxipride Hydrochloride Anhydrous;(S)-Remoxipride Hydrochloride

H2O:100 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years