1-Deazaadenosine is a highly potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the highly potential to be a chemotherapy agent for lymphoproliferative disorders. References: [1]. Cristalli G, et al.Adenosine deaminase inhibitors: Structure-activity relationships in 1-deazaadenosine and erythro-9-(2-hydroxy-3-nonyl)adenine analogues. Drug Dev.Res.
[2]. Cristalli G, et al.Improved synthesis and antitumor activity of 1-deazaadenosine.J Med Chem. 1987 Sep;30(9):1686-8.
纯度:≥98%
CAS:14432-09-8